What is it used for?

• Short-term (two to four weeks only) treatment of severe anxiety, including anxiety associated with depression, that is disabling or subjecting the individual to unacceptable distress.

How does it work?

Xanax tablets contain the active ingredient alprazolam, which is a type of medicine called a benzodiazepine. Alprazolam tablets are also available without a brand name, ie as the generic medicine. Benzodiazepines are used for their sedative and anxiety-relieving effects.

Benzodiazepines work by acting on receptors in the brain called GABA receptors. This causes the release of a neurotransmitter called GABA (gamma amino butyric acid) in the brain.

Neurotransmitters are chemicals that are stored in nerve cells in the brain and nervous system. They are involved in transmitting messages between the nerve cells. GABA is a neurotransmitter that acts as a natural ‘nerve-calming’ agent. It helps keep the nerve activity in the brain in balance, and is involved in inducing sleepiness, reducing anxiety and relaxing muscles.

Alprazolam increases the activity of GABA in the brain and therefore increases its calming effect. This helps decrease anxiety and also causes drowsiness and relaxation of muscles.

Alprazolam is used for the treatment of severe anxiety, including anxiety associated with depression. It should only be used when the disorder is severe, disabling or subjecting the individual to extreme distress. It is only suitable for short-term use, as the medicine has a high potential for dependence and addiction.

Alprazolam remains active in the body for many hours and, as a result, any drowsiness it causes may last into the next day.

How do I take it?

• Xanax tablets can be taken either with or without food. They should be swallowed with a drink.
• Always take the medicine as directed by your doctor. Do not exceed the dose prescribed by your doctor.
• The body rapidly becomes used to benzodiazepine drugs and they can be addictive. As a result, they are useful for short-term help (two to four weeks), but should not generally be used for longer periods.
• Treatment with this medicine should be stopped gradually by slowly reducing the dose, following the instructions given by your doctor. This is because suddenly stopping treatment can cause withdrawal symptoms such as headaches, muscle pain, restlessness, confusion, sweating, tremor, loss of appetite, difficulty sleeping, irritability, severe anxiety, sensitivity to light, noise or physical contact, hallucinations or convulsions. These can be avoided by stopping treatment slowly.

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